Article
Identifying Risk Genes and Interpreting Pathogenesis for Parkinson's Disease by a Multiomics Analysis.
Genes - 21 Sept 2020
Cheng Wen-Wen, Zhu Qiang, Zhang Hong-Yu
Abstract excerpt
Genome-wide association studies (GWAS) have identified tens of genetic variants associated with Parkinson's disease (PD). Nevertheless, the genes or DNA elements that affect traits through these genetic variations are usually undiscovered. This study was the first to combine meta-analysis GWAS data and expression data to identify PD risk genes. Four known genes, CRHR1, KANSL1, NSF and LRRC37A, and two new risk...
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