Article
A Pooling Genome-Wide Association Study Combining a Pathway Analysis for Typical Sporadic Parkinson's Disease in the Han Population of Chinese Mainland.
Molecular neurobiology - 1 Sept 2016
Hu Yakun, Deng Libing, Zhang Jie, Fang Xin, Mei Puming, Cao Xuebing, Lin Jiari, Wei Yi, Zhang Xiong, Xu Renshi
Abstract excerpt
Genome-wide association studies (GWAS) on sporadic Parkinson's disease (sPD) are mainly conducted in European and American populations at present, and the Han populations of Chinese mainland (HPCM) almost have not been studied yet. Here, we conducted a pooling GWAS combining a pathway analysis with 862,198 autosomal single nucleotide polymorphisms of IlluminaHumanOmniZhongHua-8 in 250 sPD and 250 controls from...
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