Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative analysis of DNA methylation and gene expression data for the diagnosis and underlying mechanism of Parkinson’s disease

18 Aug 2022

Abstract excerpt

Background: Parkinson's disease (PD) is the second most common progressive neurodegenerative disorder and the leading cause of disability in the daily activities. In the management of PD, accurate and specific biomarkers in blood for the early diagnosis of PD are urgently needed. DNA methylation is one of the main epigenetic mechanisms and associated with the gene expression and disease initiation of PD. We aimed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebrovascular and genetic disorders
Share to Nuclear Receptors and Signaling
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36062142
DOI: 10.3389/fnagi.2022.971528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative analysis of DNA methylation and gene expression data for the diagnosis and underlying mechanism of Parkinson’s diseasePMID 36062142Read ↗

Identification of potential blood biomarkers for Parkinson’s disease by gene expression and DNA methylation data integration analysisSemantic proximity Read ↗

Comprehensive methylation profile of CSF cfDNA revealed pathogenesis and diagnostic markers for early-onset Parkinson's disease.Semantic proximity Read ↗

DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in bloodSemantic proximity Read ↗

Correlation analysis and clinical validation of Parkinson's disease and epigenetic factor-related genes based on transcriptome dataSemantic proximity Read ↗

Distinctive patterns of DNA methylation associated with Parkinson diseaseSemantic proximity Read ↗

Multi-omics analysis reveals the genetic aging landscape of Parkinson's disease.Semantic proximity Read ↗

Gene4PD: a comprehensive genetic database of Parkinson's diseaseSemantic proximity Read ↗

Gene4PD: A Comprehensive Genetic Database of Parkinson’s DiseaseSemantic proximity Read ↗

Integrated Analysis and Identification of Novel Biomarkers in Parkinson’s DiseaseSemantic proximity Read ↗

A meta-analysis of public microarray data identifies biological regulatory networks in Parkinson's disease.Semantic proximity Read ↗

Characterization of baseline and longitudinal DNA Methylation in patients with sporadic Parkinsons diseaseSemantic proximity Read ↗

miRNAs and target genes in the blood as biomarkers for the early diagnosis of Parkinson’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.