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Article

Genetic Variation in CNS Myelination and Functional Brain Connectivity in Recombinant Inbred Mice.

Cells - 18 Sept 2020

Goudriaan Andrea, Loos Maarten, Spijker Sabine, Smit August B, Verheijen Mark H G

Abstract excerpt

Myelination greatly increases the speed of action potential propagation of neurons, thereby enhancing the efficacy of inter-neuronal communication and hence, potentially, optimizing the brain's signal processing capability. The impact of genetic variation on the extent of axonal myelination and its consequences for brain functioning remain to be determined. Here we investigated this question using a genetic...

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PMID: 32961889
DOI: 10.3390/cells9092119
PMCID: PMC7564997

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