Article
Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains.
BMC genomics - 13 Sept 2012
Parsons Michael J, Grimm Christina, Paya-Cano Jose L, Fernandes Cathy, Liu Lin, Philip Vivek M, Chesler Elissa J, Nietfeld Wilfried, Lehrach Hans, Schalkwyk Leonard C
Abstract excerpt
BACKGROUND: miRNAs are short single-stranded non-coding RNAs involved in post-transcriptional gene regulation that play a major role in normal biological functions and diseases. Little is currently known about how expression of miRNAs is regulated. We surveyed variation in miRNA abundance in the hippocampus of mouse inbred strains, allowing us to take a genetic approach to the study of miRNA regulation, which is...
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