Article

Probing the basis of disease heterogeneity in multiple sclerosis using genetically diverse mice

2024-06-04

Abstract excerpt

Multiple sclerosis (MS) is a complex disease with significant heterogeneity in disease course and progression. Genetic studies have identified numerous loci associated with MS risk, but the genetic basis of disease progression remains elusive. To address this, we leveraged the Collaborative Cross (CC), a genetically diverse mouse strain panel, and experimental autoimmune encephalomyelitis (EAE). The thirty-two CC...

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Literature Corpus work: 6ff5c43b-b03c-5d16-b3d1-5b4ed6a41bf1
DOI: 10.1101/2024.06.03.597205

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