Article
Natural variation and genetic covariance in adult hippocampal neurogenesis.
Proceedings of the National Academy of Sciences of the United States of America - 17 Jan 2006
Kempermann Gerd, Chesler Elissa J, Lu Lu, Williams Robert W, Gage Fred H
Abstract excerpt
Adult hippocampal neurogenesis is highly variable and heritable among laboratory strains of mice. Adult neurogenesis is also remarkably plastic and can be modulated by environment and activity. Here, we provide a systematic quantitative analysis of adult hippocampal neurogenesis in two large genetic reference panels of recombinant inbred strains (BXD and AXB/BXA, n = 52 strains). We combined data on variation in...
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