Article
Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice.
Genes, brain, and behavior - 1 Mar 2014
Ye R, Carneiro A M D, Airey D, Sanders-Bush E, Williams R W, Lu L, Wang J, Zhang B, Blakely R D
Abstract excerpt
The biogenic amine serotonin (5-HT, 5-hydroxytryptamine) exerts powerful, modulatory control over multiple physiological functions in the brain and periphery, ranging from mood and appetite to vasoconstriction and gastrointestinal motility. In order to gain insight into shared and distinct molecular and phenotypic networks linked to variations in 5-HT homeostasis, we capitalized on the stable genetic variation...
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