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Article

Biological Role of Arrestin-1 Oligomerization.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Oct 2020

Samaranayake Srimal, Vishnivetskiy Sergey A, Shores Camilla R, Thibeault Kimberly C, Kook Seunghyi, Chen Jeannie, Burns Marie E, Gurevich Eugenia V, Gurevich Vsevolod V

Abstract excerpt

Members of the arrestin superfamily have great propensity of self-association, but the physiological significance of this phenomenon is unclear. To determine the biological role of visual arrestin-1 oligomerization in rod photoreceptors, we expressed mutant arrestin-1 with severely impaired self-association in mouse rods and analyzed mice of both sexes. We show that the oligomerization-deficient mutant is capable...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32948676
DOI: 10.1523/JNEUROSCI.0749-20.2020
PMCID: PMC7574651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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