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Article

locStra: Fast analysis of regional/global stratification in whole-genome sequencing studies.

Genetic epidemiology - 1 Feb 2021

Hahn Georg, Lutz Sharon M, Hecker Julian, Prokopenko Dmitry, Cho Michael H, Silverman Edwin K, Weiss Scott T, Lange Christoph

Abstract excerpt

locStra is an R -package for the analysis of regional and global population stratification in whole-genome sequencing (WGS) studies, where regional stratification refers to the substructure defined by the loci in a particular region on the genome. Population substructure can be assessed based on the genetic covariance matrix, the genomic relationship matrix, and the unweighted/weighted genetic Jaccard similarity...

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Identifiers

PMID: 32929743
DOI: 10.1002/gepi.22356
PMCID: PMC7856019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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