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Article

Similarity-Based Analysis of Allele Frequency Distribution among Multiple Populations Identifies Adaptive Genomic Structural Variants.

Molecular biology and evolution - 2 Mar 2022

Saitou Marie, Masuda Naoki, Gokcumen Omer

Abstract excerpt

Structural variants have a considerable impact on human genomic diversity. However, their evolutionary history remains mostly unexplored. Here, we developed a new method to identify potentially adaptive structural variants based on a similarity-based analysis that incorporates genotype frequency data from 26 populations simultaneously. Using this method, we analyzed 57,629 structural variants and identified 576...

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Share to Alleles
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34718708
DOI: 10.1093/molbev/msab313
PMCID: PMC8896759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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