Article

FounderRare: A Novel Statistical Package to Identify Rare Variants in Complex Diseases

2025-09-12

Abstract excerpt

FounderRare is a statistical package designed for the identification of rare variants in complex diseases. It leverages population genealogies, including those shaped by founder effects and identity-by-descent (IBD) segments, distinguishing it from other tools. This paper serves as a theoretical guide to the FounderRare package, illustrating its operations and capabilities. The package implements an IBD-based appr...

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Literature Corpus work: 42f52bc4-fda8-5421-928d-8e991fa38ca5
DOI: 10.1101/2025.09.11.25335516

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