Article
Genetic association studies with bivariate mixed responses subject to measurement error and misclassification.
Statistics in medicine - 20 Nov 2020
Zhang Qihuang, Yi Grace Y
Abstract excerpt
In genetic association studies, mixed effects models have been widely used in detecting the pleiotropy effects which occur when one gene affects multiple phenotype traits. In particular, bivariate mixed effects models are useful for describing the association of a gene with a continuous trait and a binary trait. However, such models are inadequate to feature the data with response mismeasurement, a characteristic...
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