Article
Genetic variance components analysis for binary phenotypes using generalized linear mixed models (GLMMs) and Gibbs sampling.
Genetic epidemiology - 1 Jan 1999
Burton P R, Tiller K J, Gurrin L C, Cookson W O, Musk A W, Palmer L J
Abstract excerpt
The common complex diseases such as asthma are an important focus of genetic research, and studies based on large numbers of simple pedigrees ascertained from population-based sampling frames are becoming commonplace. Many of the genetic and environmental factors causing these diseases are unknown and there is often a strong residual covariance between relatives even after all known determinants are taken into...
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