Article
A likelihood-based approach to mixed modeling with ambiguity in cluster identifiers.
Biostatistics (Oxford, England) - 1 Oct 2008
Foulkes Andrea S, Yucel Recai, Li Xiaohong
Abstract excerpt
This manuscript describes a novel, linear mixed-effects model-fitting technique for the setting in which correlated data indicators are not completely observed. Mixed modeling is a useful analytical tool for characterizing genotype-phenotype associations among multiple potentially informative genetic loci. This approach involves grouping individuals into genetic clusters, where individuals in the same cluster...
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