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Article

Guidance for the utility of linear models in meta-analysis of genetic association studies of binary phenotypes.

European journal of human genetics : EJHG - 1 Feb 2017

Cook James P, Mahajan Anubha, Morris Andrew P

Abstract excerpt

Linear mixed models are increasingly used for the analysis of genome-wide association studies (GWAS) of binary phenotypes because they can efficiently and robustly account for population stratification and relatedness through inclusion of random effects for a genetic relationship matrix. However, the utility of linear (mixed) models in the context of meta-analysis of GWAS of binary phenotypes has not been...

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Identifiers

PMID: 27848946
DOI: 10.1038/ejhg.2016.150
PMCID: PMC5237383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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