Article
PNPLA3 rs738409 C>G Variant Predicts Fibrosis Progression by Noninvasive Tools in Nonalcoholic Fatty Liver Disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2021
Pennisi Grazia, Pipitone Rosaria Maria, Cammà Calogero, Di Marco Vito, Di Martino Vincenzo, Spatola Federica, Zito Rossella, Craxì Antonio, Grimaudo Stefania, Petta Salvatore
Abstract excerpt
Liver fibrosis is the main predictor of events in patients with nonalcoholic fatty liver disease (NAFLD),1 and its evolution is characterized by a nonlinear trend2,3 mostly affected by metabolic risk factors, severity of liver inflammation and steatosis, and weight loss.3 The rs738409 C>G common variant in PNPLA3 gene has been associated with severity of fibrosis and risk of liver-related events in NAFLD.4,5...
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