Article
Effect of PNPLA3 polymorphism on diagnostic performance of various noninvasive markers for diagnosing and staging nonalcoholic fatty liver disease.
Journal of gastroenterology and hepatology - 1 Jun 2020
Liu Wen-Yue, Zheng Kenneth I, Pan Xiao-Yan, Ma Hong-Lei, Zhu Pei-Wu, Wu Xi-Xi, Rios Rafael S, Targher Giovanni, Byrne Christopher D, Wang Xiao-Dong, Chen Yong-Ping, Zheng Ming-Hua
Abstract excerpt
BACKGROUND AND AIM: Patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M (rs738409) genotype influences clinical/biochemical characteristics in patients with nonalcoholic fatty liver disease (NAFLD), but whether PNPLA3-I148M (rs738409) genotype also influences the diagnostic performance of noninvasive diagnostic tests for NAFLD is uncertain. Our aim was to investigate the differences in...
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