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Article

Long-Term Effect of PNPLA3 on the Aggravation of Nonalcoholic Fatty Liver Disease in a Biopsy-Proven Cohort.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Apr 2023

Koo Bo Kyung, Lee Hyunsuk, Kwak Soo-Heon, Lee Dong Hyeon, Park Jeong Hwan, Kim Won

Abstract excerpt

The PNPLA3 rs738409 G allele increases the risk of not only nonalcoholic fatty liver disease (NAFLD) but also nonalcoholic steatohepatitis (NASH) or fibrosis.1 It also affects the prognosis of patients with NAFLD in specific conditions. After liver transplantation, patients with NAFLD carrying the rs738409 GG genotype have a higher risk of graft steatosis2 or development of hepatocellular carcinoma.3 In addition,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35189385
DOI: 10.1016/j.cgh.2022.02.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Long-Term Effect of PNPLA3 on the Aggravation of Nonalcoholic Fatty Liver Disease in a Biopsy-Proven Cohort.PMID 35189385Read ↗

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Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.Semantic proximity Read ↗

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