A 4-polymorphism risk score predicts steatohepatitis in children with nonalcoholic fatty liver disease.

Abstract excerpt

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in industrialized countries in adults and children, following the trail of the epidemic diffusion of obesity. Nonalcoholic steatohepatitis (NASH) is a potentially serious form of NAFLD linked with a significant increase in overall and liver-related morbidity and mortality. Because diagnosis still requires...

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• Biopsy
• Kruppel-Like Transcription Factors
• Lipase
• Logistic Models
• Non-alcoholic Fatty Liver Disease