Article
Interactive effect of TLR SNPs and exposure to sexually transmitted infections on prostate cancer risk in Jamaican men.
The Prostate - 1 Nov 2020
Dubey Bhawna, Jackson Maria, Zeigler-Johnson Charnita, Devarajan Karthik, Flores-Obando Rafael E, McFarlane-Anderson Norma, Tulloch-Reid Marshall, Aiken William, Kimbro Kevin, Reed Dominique, Kidd LaCreis R, Gibbs Denise, Kumar Sudhir, Ragin Camille
Abstract excerpt
BACKGROUND: Prostate cancer (PC) risk increases with African ancestry and a history of sexually transmitted infections (STIs). Also, single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes influence PC risk. This pilot study explores interactions between STIs and TLR-related SNPs in relation to PC risk among Jamaican men. METHODS: This case-control study evaluates two TLR related SNPs in 356...
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