Article
Prospective study of effect modification by Toll-like receptor 4 variation on the association between Trichomonas vaginalis serostatus and prostate cancer.
Cancer causes & control : CCC - 1 Jan 2013
Chen Yen Ching, Huang Yi Ling, Platz Elizabeth A, Alderete John F, Zheng Lu, Rider Jennifer R, Kraft Peter, Giovannucci Edward, Sutcliffe Siobhan
Abstract excerpt
PURPOSE: In previous studies, we observed a positive association between Trichomonas vaginalis serostatus and risk of prostate cancer, particularly aggressive cancer, which we hypothesized might be due to T. vaginalis-mediated intraprostatic inflammation and cell damage. To explore this hypothesis further, we investigated effect modification by Toll-like receptor 4 (TLR4) variation on this association. We...
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