Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A pilot study on prostate cancer risk and pro-inflammatory genotypes: pathophysiology and therapeutic implications.

Current pharmaceutical design - 1 Jan 2010

Balistreri C R, Caruso C, Carruba G, Miceli V, Campisi I, Listì F, Lio D, Colonna-Romano G, Candore G

Abstract excerpt

Host genetic factors are crucial risk determinants for many human cancers. In this framework, an interesting model is represented by prostate cancer (PC), which is featured by a complex pathophysiology with a strong genetic component. Multiple genes seem to influence PC risk and several single nucleotide polymorphisms (SNPs) of candidate genes modifying PC susceptibility have been identified. It is noteworthy the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Inflammation Mediators

Share to Pilot Projects

Share to Polymorphism, Single Nucleotide

Share to Prostatic Neoplasms

Share to Risk Factors

Source

Identifiers

PMID: 20388081
DOI: 10.2174/138161210790883877

Genes

PTGS2
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pilot study on prostate cancer risk and pro-inflammatory genotypes: pathophysiology and therapeutic implications.PMID 20388081Read ↗

Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach.Semantic proximity Read ↗

Prostate cancer: from the pathophysiologic implications of some genetic risk factors to translation in personalized cancer treatments.Semantic proximity Read ↗

CCR5 proinflammatory allele in prostate cancer risk: a pilot study in patients and centenarians from Sicily .Semantic proximity Read ↗

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Genotyping of sex hormone-related pathways in benign and malignant human prostate tissues: data of a preliminary study.Semantic proximity Read ↗

Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study.Semantic proximity Read ↗

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.Semantic proximity Read ↗

Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.Semantic proximity Read ↗

Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer.Semantic proximity Read ↗

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.Semantic proximity Read ↗

Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.Semantic proximity Read ↗

A comprehensive association study for genes in inflammation pathway provides support for their roles in prostate cancer risk in the CAPS study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.