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Chromosomal Rearrangements of Synthetic Yeast by SCRaMbLE.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Luo Zhouqing, Jiang Shuangying, Dai Junbiao

Abstract excerpt

Diversified genomes derived from chromosomal rearrangements are valuable materials for evolution. Naturally, chromosomal rearrangements occur at extremely low frequency to ensure genome stability. In the synthetic yeast genome project (Sc2.0), an inducible chromosome rearrangement system named Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) is built to produce chromosomal...

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PMID: 32889719
DOI: 10.1007/978-1-0716-0868-5_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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