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Article

Discovering and genotyping genomic structural variations by yeast genome synthesis and inducible evolution.

FEMS yeast research - 1 Mar 2020

Chen Si, Xie Ze-Xiong, Yuan Ying-Jin

Abstract excerpt

Genomic structural variations (SVs) promote the evolution of Saccharomyces cerevisiae, and play an important role in phenotypic diversities. Yeast genomic structures can be remodeled by design and bottom-up synthesis. The synthesis of yeast genome creates novel copy number variations (CNVs) and SVs and develops new strategies to discover gene functions. Further, an inducible evolution system SCRaMbLE, consisted...

Topics

Directed Molecular Evolution
Genome, Fungal
Genomic Structural Variation
Genotype
Phenotype
Saccharomyces cerevisiae

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32188997
DOI: 10.1093/femsyr/foaa012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32188997-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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