Article
Age at Onset of LRRK2 p.Gly2019Ser Is Related to Environmental and Lifestyle Factors.
Movement disorders : official journal of the Movement Disorder Society - 1 Oct 2020
Lüth Theresa, König Inke R, Grünewald Anne, Kasten Meike, Klein Christine, Hentati Faycel, Farrer Matthew, Trinh Joanne
Abstract excerpt
OBJECTIVES: The effect of environmental and lifestyle factors on patients with LRRK2 (leucine-rich repeat kinase 2) p.Gly2019Ser (LRRK2+ /PD+ ) compared to idiopathic PD (iPD) has yet to be thoroughly investigated. METHODS: In a homogeneous Tunisian Arab Berber population, we recruited 200 idiopathic PD and 199 LRRK2 p.Gly2019Ser mutation carriers, of whom 142 had PD (LRRK2+ /PD+ ) and 57 were unaffected (LRRK2+...
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