Article
Genetic and Environmental Factors Influence Pleomorphy of lRRK2 Parkinsonism
2020-12-23
Abstract excerpt
Missense mutations in the LRRK2 gene were first identified as a pathogenic cause of Parkinson’s disease (PD) in 2004. Soon thereafter, a founder mutation in LRRK2, p.Gly2019Ser (rs34637584), was described, and it is now estimated that there are approximately 100,000 people worldwide that carry this risk variant. While the clinical presentation of LRRK2 parkinsonism has been largely indistinguishable from spo...
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Identifiers and source
- Literature Corpus work
- 84e7cd6f-80c0-5b33-a288-6b2b0dac1f21
- DOI
- 10.20944/preprints202012.0584.v1