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Interaction of mitochondrial polygenic score and environmental factors in LRRK2 p.Gly2019Ser parkinsonism

2023-01-03

Abstract excerpt

The objective of our study was to investigate the impact of the mitochondrial polygenic score (MGS) and lifestyle/environmental data on age at onset in LRRK2 p.Gly2019Ser parkinsonism ( LRRK2 -PD) and idiopathic Parkinson’s disease (iPD). In this study, we included N=486 patients with LRRK2 -PD and N=9259 patients with iPD from AMP-PD, Fox Insight, and a Tunisian Arab-Berber founder population. Genotyping data was...

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Literature Corpus work
a1b0fde3-c9f5-53ea-8932-c127ef543949
DOI
10.1101/2023.01.02.23284113
Open publication

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Interaction of mitochondrial polygenic score and environmental factors in LRRK2 p.Gly2019Ser parkinsonismDOI 10.1101/2023.01.02.23284113
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