Article
Transcriptomic Heterogeneity of Alzheimer's Disease Associated with Lipid Genetic Risk.
Neuromolecular medicine - 1 Dec 2020
Miao Xiao, Liu Weifeng, Fan Bin, Lin Honghuang
Abstract excerpt
Alzheimer's disease (AD) is a multifactorial disease that affects more than 5 million Americans. Multiple pathways might be involved in the AD pathogenesis. The implication of lipid genetic susceptibility on brain gene expression is yet to be investigated. The current study included 192 brain samples from AD patients who were enrolled in the ROSMAP study. The samples were genotyped and imputed to the...
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