Article
The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).
PloS one - 1 Jan 2020
Yobi Doudou Malekita, Kayiba Nadine Kalenda, Mvumbi Dieudonné Makaba, Boreux Raphael, Bontems Sebastien, Kabututu Pius Zakayi, De Mol Patrick, Speybroeck Niko, Mvumbi Georges Lelo, Hayette Marie-Pierre
Abstract excerpt
Artemisinin-based combination therapies (ACTs) have been recommended by the World Health Organization (WHO) as first-line treatment of uncomplicated Plasmodium falciparum (P. falciparum) malaria since 2005 in Democratic Republic of Congo (DRC) and a regular surveillance of the ACT efficacy is required to ensure the treatment effectiveness. Mutations in the propeller domain of the pfk13 gene were identified as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
