Article
Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.
Emerging infectious diseases - 1 Mar 2015
Isozumi Rie, Uemura Haruki, Kimata Isao, Ichinose Yoshio, Logedi John, Omar Ahmeddin H, Kaneko Akira
Abstract excerpt
We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012-2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.
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