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Emergence of Mutations in the K13 Propeller Gene of Plasmodium falciparum Isolates from Dakar, Senegal, in 2013-2014.

Antimicrobial agents and chemotherapy - 1 Jan 2016

Boussaroque Agathe, Fall Bécaye, Madamet Marylin, Camara Cheikhou, Benoit Nicolas, Fall Mansour, Nakoulima Aminata, Dionne Pierre, Fall Kadidiatou Ba, Diatta Bakary, Diémé Yaya, Wade Boubacar, Pradines Bruno

Abstract excerpt

The kelch 13 (K13) propeller gene is associated with artemisinin resistance. In a previous work, there were no mutations found in 138 Plasmodium falciparum isolates collected in 2012 and 2013 from patients residing in Dakar, Senegal (M. Torrentino-Madamet et al., Malar J 13:472, 2014, http://dx.doi.org/10.1186/1475-2875-13-472). However, the N554H, Q613H, and V637I mutations were identified in the propeller...

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PMID: 26503652
DOI: 10.1128/AAC.01346-15
PMCID: PMC4704212

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Source receipt: pubmed, retrieved 7 Sept 2026.

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