Article
K13 Propeller Mutations in Plasmodium falciparum Populations in Regions of Malaria Endemicity in Vietnam from 2009 to 2016.
Antimicrobial agents and chemotherapy - 1 Apr 2017
Thuy-Nhien Nguyen, Tuyen Nguyen Kim, Tong Nguyen Thanh, Vy Nguyen Tuong, Thanh Ngo Viet, Van Huynh Thuy, Huong-Thu Pham, Quang Huynh Hong, Boni Maciej F, Dolecek Christiane, Farrar Jeremy, Thwaites Guy E, Miotto Olivo, White Nicholas J, Hien Tran Tinh
Abstract excerpt
The spread of artemisinin-resistant Plasmodium falciparum compromises the therapeutic efficacy of artemisinin combination therapies (ACTs) and is considered the greatest threat to current global initiatives to control and eliminate malaria. This is particularly relevant in Vietnam, where dihydroartemisinin-piperaquine (DP) is the recommended ACT for P. falciparum infection. The propeller domain gene of K13, a...
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