Article
Genomic and epigenetic aberrations of chromosome 1p36.13 have prognostic implications in malignancies.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology - 1 Dec 2020
Naderi Ali
Abstract excerpt
Deletions of chromosome 1p36 are common in malignancies; however, there is limited information regarding the biological and prognostic implications of 1p36 in cancer. Steroid Receptor-Associated and Regulated Protein (SRARP) is a tumor suppressor on chromosome 1p36.13 that its inactivation predicts poor cancer outcome, indicating that the 1p36.13 segment requires further studies. Therefore, a comprehensive...
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