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Identification of methylation-driven genes related to the prognosis of papillary renal cell carcinoma: a study based on The Cancer Genome Atlas

12 Jun 2020

Abstract excerpt

BACKGROUND: Aberrant DNA methylation patterns are involved in the pathogenesis of papillary renal cell carcinoma (pRCC). This study aimed to investigate the potential of methylation-driven genes as biomarkers in determining the prognosis of pRCC by bioinformatics analysis. METHODS: DNA methylation and transcriptome profiling data were downloaded from The Cancer Genome Atlas database. Methylation-driven genes...

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Share to Epigenetics and DNA Methylation
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PMID: 32536823
DOI: 10.1186/s12935-020-01331-7

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