Article

Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers

2018-12-18

Abstract excerpt

The integration of genomic and DNA methylation data has been demonstrated as a powerful strategy in understanding cancer mechanisms and identifying therapeutic targets. The TCGA consortium has mapped DNA methylation in thousands of cancer samples using Illumina Infinium Human Methylation 450K BeadChip (Illumina 450K array) that only covers about 1.5% of CpGs in the human genome. Therefore, increasing the coverage...

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Literature Corpus work: 9db08831-8b29-53c0-b9ff-eeee7186b882
DOI: 10.1101/491845

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