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Article

SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies.

Molecular oncology - 1 May 2018

Naderi Ali

Abstract excerpt

Deletions of chromosome 1p36 are common in cancers; however, despite extensive studies, there has been limited success for discovering candidate tumor suppressors in this region. SRARP has recently been identified as a novel corepressor of the androgen receptor (AR) and is located on chromosome 1p36. Here, bioinformatics analysis of large tumor datasets was performed to study SRARP and its gene pair, HSPB7. In...

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Topics

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Share to Chromosomes, Human
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Gene Silencing

Share to Genes, Tumor Suppressor

Share to HSP27 Heat-Shock Proteins

Share to Molecular Sequence Annotation

Source

Open in PubMed Open full text

Identifiers

PMID: 29577611
DOI: 10.1002/1878-0261.12195
PMCID: PMC5928383

Genes

SRARP
HSPB7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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