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A population approach of rifampicin pharmacogenetics and pharmacokinetics in Mexican patients with tuberculosis.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2020

Medellin-Garibay Susanna Edith, Huerta-García Ana Patricia, Rodríguez-Báez Ana Socorro, Magaña-Aquino Martín, Ortiz-Álvarez Arturo, Portales-Pérez Diana Patricia, Milán-Segovia Rosa Del Carmen, Romano-Moreno Silvia

Abstract excerpt

The aim of this study was to develop a population pharmacokinetic model of rifampicin (RMP) in Mexican patients with tuberculosis (TB) to evaluate the influence of anthropometric and clinical covariates, as well as genotypic variants associated with MDR1 and OATP1B1 transporters. A prospective study approved by Research Ethics Committee was performed at Hospital Central in San Luis Potosí, Mexico. TB patients...

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Identifiers

PMID: 32810723
DOI: 10.1016/j.tube.2020.101982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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