Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relation between APOE genotype and cerebral microbleeds in cognitively unimpaired middle- and old-aged individuals.

Neurobiology of aging - 1 Nov 2020

Ingala Silvia, Mazzai Linda, Sudre Carole H, Salvadó Gemma, Brugulat-Serrat Anna, Wottschel Viktor, Falcon Carles, Operto Grégory, Tijms Betty, Gispert Juan Domingo, Molinuevo José Luis, Barkhof Frederik

Abstract excerpt

Positive associations between cerebral microbleeds (CMBs) and APOE-ε4 (apolipoprotein E) genotype have been reported in Alzheimer's disease, but show conflicting results. We investigated the effect of APOE genotype on CMBs in a cohort of cognitively unimpaired middle- and old-aged individuals enriched for APOE-ε4 genotype. Participants from ALFA (Alzheimer and Families) cohort were included and their magnetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Cerebral Hemorrhage

Share to Cognition

Share to Homozygote

Share to Magnetic Resonance Imaging

Share to White Matter

Source

Identifiers

PMID: 32791423
DOI: 10.1016/j.neurobiolaging.2020.06.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relation between APOE genotype and cerebral microbleeds in cognitively unimpaired middle- and old-aged individuals.PMID 32791423Read ↗

Genetic associations with brain microbleeds: Systematic review and meta-analyses.Semantic proximity Read ↗

APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.Semantic proximity Read ↗

Apolipoprotein E genotype influences spatial distribution of cerebral microbleeds.Semantic proximity Read ↗

Associations between APOE genotype and cerebral small-vessel disease: a longitudinal study.Semantic proximity Read ↗

Apolipoprotein E Genotype and Cerebrovascular Alterations Can Influence Conversion to Dementia in Patients with Mild Cognitive ImpairmentSemantic proximity Read ↗

Relationship between APOE Genotype Status and Imaging Features in Patients with Alzheimer Disease Being Considered for Antiamyloid β Therapy.Semantic proximity Read ↗

Association of common genetic variants with brain microbleeds: A genome-wide association study.Semantic proximity Read ↗

APOE-related biomarker profiles in non-pathological aging and early phases of Alzheimer's disease.Semantic proximity Read ↗

The role of APOE in cerebrovascular dysfunction.Semantic proximity Read ↗

Cerebral microbleeds in the population based AGES-Reykjavik study: prevalence and location.Semantic proximity Read ↗

APOE4 and cognition in intracranial atherosclerosis: beyond Alzheimer's pathology.Semantic proximity Read ↗

The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.