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Article

Associations between APOE genotype and cerebral small-vessel disease: a longitudinal study.

Oncotarget - 4 Jul 2017

Luo Xiao, Jiaerken Yerfan, Yu Xinfeng, Huang Peiyu, Qiu Tiantian, Jia Yunlu, Li Kaicheng, Xu Xiaojun, Shen Zhujing, Guan Xiaojun, Zhou Jiong, Zhang Minming, Adni For The Alzheimer's Disease Neuroimaging Initiative

Abstract excerpt

OBJECTIVE: It remains unclear if and how the interactions between APOE genotypes and cerebral small-vessel diseases (CSVD) lead to cognitive decline in the long term. Based on ADNI cohort, this longitudinal study aimed to clarify the potential relationship among APOE genotype, CSVD and cognition by integrating multi-level data. METHOD: There were 135 healthy elderly (including ε2, ε4 allele carriers and ε3...

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Identifiers

PMID: 28574812
DOI: 10.18632/oncotarget.17724
PMCID: PMC5546495

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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