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Article

Relationship between APOE Genotype Status and Imaging Features in Patients with Alzheimer Disease Being Considered for Antiamyloid β Therapy.

AJNR. American journal of neuroradiology - 4 Mar 2026

Vejdani-Jahromi Maryam, Calle Esteban, Ganem Odette, Rohatgi Saurabh, Farzaneh Hana, Griffin Harry, Zhu Shenghua, Seah Jarrel, Omid-Fard Nima, Kozak Benjamin, Ford Jeremy, Romero Javier M

Abstract excerpt

BACKGROUND AND PURPOSE: Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease progression. However, their use is occasionally associated with amyloid-related imaging abnormalities (ARIA), posing prominent clinical challenges. It has been shown that apolipoprotein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41781178
DOI: 10.3174/ajnr.A9056
PMCID: PMC12964434

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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