Article
The same but different: multiple functions of the fungal flavin dependent monooxygenase SorD from Penicillium chrysogenum.
Chemical communications (Cambridge, England) - 21 Sept 2020
Kahlert Lukas, Cox Russell J, Skellam Elizabeth
Abstract excerpt
Sorbicillinoids are a large family of fungal secondary metabolites with a diverse range of structures and numerous bioactivites, some of which have pharmaceutical potential. The flavin-dependent monooxygenase SorD from Penicillium chrysogenum (PcSorD) utilizes sorbicillinol to catalyze a broad scope of reactions: formation of oxosorbicillinol and epoxysorbicillinol; intermolecular Diels-Alder and Michael-addition...
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