Article
Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function
1 Jan 2017
Abstract excerpt
Covering: up to January 2017Cytochrome P450 enzymes (P450s) are some of the most exquisite and versatile biocatalysts found in nature. In addition to their well-known roles in steroid biosynthesis and drug metabolism in humans, P450s are key players in natural product biosynthetic pathways. Natural products, the most chemically and structurally diverse small molecules known, require an extensive collection of...
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