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Article

Structural insights into the metabolism of 2-chlorodibenzofuran by an evolved biphenyl dioxygenase.

Biochemical and biophysical research communications - 18 May 2012

Kumar Pravindra, Mohammadi Mahmood, Dhindwal Sonali, Pham Thi Thanh My, Bolin Jeffrey T, Sylvestre Michel

Abstract excerpt

The biphenyl dioxygenase of Burkholderia xenovorans LB400 (BphAE(LB400)) is a Rieske-type oxygenase that catalyzes the stereospecific oxygenation of many heterocyclic aromatics including dibenzofuran. In a previous work, we evolved BphAE(LB400) and obtained BphAE(RR41). This variant metabolizes d...

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PMID: 22546558
DOI: 10.1016/j.bbrc.2012.04.078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22546558-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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