Article
Mendelian randomisation approaches to the study of prenatal exposures: A systematic review.
Paediatric and perinatal epidemiology - 1 Jan 2021
Diemer Elizabeth W, Labrecque Jeremy A, Neumann Alexander, Tiemeier Henning, Swanson Sonja A
Abstract excerpt
BACKGROUND: Mendelian randomisation (MR) designs apply instrumental variable techniques using genetic variants to study causal effects. MR is increasingly used to evaluate the role of maternal exposures during pregnancy on offspring health. OBJECTIVES: We review the application of MR to prenatal exposures and describe reporting of methodologic challenges in this area. DATA SOURCES: We searched PubMed, EMBASE,...
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