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Article

Usefulness of Mendelian randomization in observational epidemiology.

International journal of environmental research and public health - 1 Mar 2010

Bochud Murielle, Rousson Valentin

Abstract excerpt

Mendelian randomization refers to the random allocation of alleles at the time of gamete formation. In observational epidemiology, this refers to the use of genetic variants to estimate a causal effect between a modifiable risk factor and an outcome of interest. In this review, we recall the principles of a "Mendelian randomization" approach in observational epidemiology, which is based on the technique of...

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PMID: 20616999
DOI: 10.3390/ijerph7030711
PMCID: PMC2872313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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