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Genome-wide pQTL analysis of protein expression regulatory networks in the human liver

10 Aug 2020

Abstract excerpt

BACKGROUND: Previous expression quantitative trait loci (eQTL) studies have identified thousands of genetic variants to be associated with gene expression at the mRNA level in the human liver. However, protein expression often correlates poorly with mRNA levels. Thus, protein quantitative trait loci (pQTL) study is required to identify genetic variants that regulate protein expression in human livers. RESULTS: We...

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PMID: 32778093
DOI: 10.1186/s12915-020-00830-3

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