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Article

A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver.

Scientific reports - 12 Apr 2018

Strunz Tobias, Grassmann Felix, Gayán Javier, Nahkuri Satu, Souza-Costa Debora, Maugeais Cyrille, Fauser Sascha, Nogoceke Everson, Weber Bernhard H F

Abstract excerpt

Genome-wide association studies (GWAS) have identified numerous genetic variants in the human genome associated with diseases and traits. Nevertheless, for most loci the causative variant is still unknown. Expression quantitative trait loci (eQTL) in disease relevant tissues is an excellent approach to correlate genetic association with gene expression. While liver is the primary site of gene transcription for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29650998
DOI: 10.1038/s41598-018-24219-z
PMCID: PMC5897392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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