Article
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.
PLoS genetics - 1 May 2011
Innocenti Federico, Cooper Gregory M, Stanaway Ian B, Gamazon Eric R, Smith Joshua D, Mirkov Snezana, Ramirez Jacqueline, Liu Wanqing, Lin Yvonne S, Moloney Cliona, Aldred Shelly Force, Trinklein Nathan D, Schuetz Erin, Nickerson Deborah A, Thummel Ken E, Rieder Mark J, Rettie Allan E, Ratain Mark J, Cox Nancy J, Brown Christopher D
Abstract excerpt
The discovery of expression quantitative trait loci ("eQTLs") can help to unravel genetic contributions to complex traits. We identified genetic determinants of human liver gene expression variation using two independent collections of primary tissue profiled with Agilent (n = 206) and Illumina (n = 60) expression arrays and Illumina SNP genotyping (550K), and we also incorporated data from a published study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.