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Article

Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data.

Neurobiology of aging - 1 Nov 2020

Cong Shan, Yao Xiaohui, Huang Zhi, Risacher Shannon L, Nho Kwangsik, Saykin Andrew J, Shen Li

Abstract excerpt

Medial temporal lobe (MTL) consists of hippocampal subfields and neighboring cortices. These heterogeneous structures are differentially involved in memory, cognitive and emotional functions, and present nonuniformly distributed atrophy contributing to cognitive disorders. This study aims to examine how genetics influences Alzheimer's disease (AD) pathogenesis via MTL substructures by analyzing high-resolution...

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Identifiers

PMID: 32768867
DOI: 10.1016/j.neurobiolaging.2020.07.005
PMCID: PMC7609616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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